On Friday, we sent the modified version of the proposal to the Research Executive Agency. It was quite an exhausting work so I'm tired a little bit. Now, we are just waiting for the positive consideration...The outlined project is completely different from the original one. The disease of interest has been changed from multiple myeloma to acute lymphoblastic leukemia (ALL) which was quite reasonable since I already have some experience in ALL research (five papers in international journals) and my host group is absolutely in the forefront regarding this field. My current supervisor and his colleagues discovered in the '90s that the ALL, which is the most common cancer in childhood, may be originated in utero (before birth). They investigated monozygotic twin pairs concordant for ALL and found the same genetic aberration in both co-twins for which the most plausible explanation is that the first genetic event of the multi-step generation of the leukemia (leukemogenesis) occured in one twin and metastatised to the other co-twin via the shared circulation. I hope you also find it interesting...